![]() Unconjugated bilirubin is metabolised in the liver to produce conjugated (or ‘direct’) bilirubin, which passes into the gut and is largely excreted in stool.( 1) HOW RELEVANT IS THIS TO MY PRACTICE? Most of the unconjugated (or ‘indirect’) bilirubin formed is bound to albumin as it circulates, although some bilirubin is ‘free’ and hence able to enter the brain. resolving cephalohaematoma), infections, liver disease, bruising and metabolic disorders.( 1) Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one common cause of severe neonatal jaundice in Singapore.( 2) Bilirubin is mainly produced by the breakdown of red blood cells. Neonatal jaundice, which refers to jaundice during the early days of life, has many aetiologies, including maternal and fetal blood group incompatibility (most commonly Rhesus or ABO incompatibility), certain causes of haemolysis (e.g. Patients present with yellow colouration of the skin and whites of the eyes. ![]() Jaundice refers to a condition caused by the accumulation of bilirubin in the skin, mucous membranes and sclerae. Mrs Tan wanted advice on what else she could do to improve Michael’s jaundice and whether exposure to the sun would help. ![]() ![]() You asked how Michael had adjusted and how everyone at home had adapted to their new roles since the birth. You reviewed the child’s health booklet and noticed that his total serum bilirubin level, from the afternoon of the day before their visit, was 119 µmol/L (7 mg/dL). She provided a letter of discharge from the hospital where Michael was delivered. Mrs Tan took her three-day-old child, Michael, to your clinic for a review of his neonatal jaundice. The importance of stool colour examination and its role in early detection of cholestatic jaundice is emphasised. They include clinical assessment of the baby’s well-being looking out for features that suggest pathological jaundice assessment for the presence of high-risk features utilising appropriate laboratory tests for monitoring assessing the degree of jaundice to decide if the child can be safely followed up in primary care and providing advice on primary prevention measures and allaying parental concerns. This article describes consultation tasks in the primary care setting with the aim of providing a guide for the safe management of neonatal jaundice. High levels of serum bilirubin can also result in bilirubin encephalopathy. However, others have pathological jaundice, which must be detected early. Most afflicted babies have physiological jaundice and their prognosis is good. Open Access This is an open access article distributed under the CC BY-NC license ( ).Neonatal jaundice is a common condition seen in the primary care setting. It is important for health workers to assess gestational age on antenatal and intranatal care to anticipate pathological jaundice and mothers need to always take their baby to health services if the baby appears to have yellow skin. Gestational age associated with pathological jaundice and maternal age is not associated with pathological jaundice. The correlation between gestational age and pathological jaundice got p value = 0.035, the correlation between maternal age with pathological jaundice got p value = 1.000. ![]() Some of neonatal (24.44%) born during pre-term gestation suffered pathologic jaundice. The result of study found that 5.1% of neonatal had post-term gestation, 21.55% of mothers delivered at risk of ages, 6.06% suffered pathologic neonatal jaundice. The analysis used Kolmogorov-Smirnov test, Fisher Exact Test. The sample consisted of 297 babies chosen using systematic random sampling technique. The research used quantitative analytical method with cross sectional approach. The main objective of this study is to analyze the correlation between gestational and maternal age with pathologic neonatal jaundice. It affects the growth of the fetus due to the immaturity of the reproductive organs. Pathologic jaundice is one of the causes of neonatal death, among the risk factor is pre-term pregnancy that causes prematurity. ![]()
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